Tsunami Run Enhanced is a 2D side-scrolling platformer made with Pyxel. The player runs through procedurally generated levels, jumps across platforms, collects coins, avoids holes and enemies, and must survive recurring tsunami waves. There are three levels with increasing difficulty: Beach, Cliffs, and Deep Sea. Later levels introduce moving platforms, crumbling platforms, and anglerfish enemies.

Throughout the game, players can collect power-ups such as Double Score, Slow Time, Low Gravity (Fly), and Shield, each providing temporary advantages. Safe platforms above the waterline can be used to avoid tsunamis, while shields protect against both enemies and waves. Coins, combo chains, score multipliers, particle effects, animations, and sound effects add variety to gameplay. Reaching an Exit Gate advances the player to the next level, and after completing all three levels, a high-score screen allows players to enter their name and record their final score.